Pharmacogenomics in Cancer Treatment: Tailoring Drug Therapy Based on Genetic Variations

Abstract

Pharmacogenomics in cancer treatment represents a pivotal shift towards personalized medicine, aiming to optimize therapeutic outcomes by leveraging individual genetic variations. This approach involves tailoring drug therapies to match patients' genetic profiles, thereby enhancing efficacy while minimizing adverse effects. By analyzing genetic markers such as single nucleotide polymorphisms (SNPs) and gene expression patterns, clinicians can predict drug response and toxicity levels more accurately. This abstract explores current advancements, challenges, and future prospects of pharmacogenomics in oncology, highlighting its potential to revolutionize cancer treatment paradigms through targeted and individualized therapies.